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Pulsed field ablation Market Report by Worldwide Market Trends & Opportunities and Forecast to 2035 Traditional thermal ablation techniques are known to cause several side-effects, which necessitates the development of non-thermal pulsed field ablation (pfa) technology to ensure patient safety and mitigate the risk of adverse effects. The Pulsed field ablation market size is anticipated to grow from US$ 185 million in 2024 to US$ 5,418 million by 2035, growing at a CAGR of 35.9% during the forecast period, till 2035. Pulsed field ablation is a non-thermal ablation technology, that destabilizes cell membrane by forming irreversible pores, consequentially leading to cell death. PFA leads to the formation of irreversible pores in target cells, rendering instability to the cell membrane, subsequently leading to cell death. A high-voltage direct current is delivered between two or more electrodes, which produces the electric field. While ablating tissues, PFA spares the extracellular matrix, averting the disruption of tissue planes, which is a key characteristic of RF damage. Several pulsed field ablation (PFA) technologies are currently being evaluated for atrial fibrillation (AF) ablation given their potential for improved procedural efficiency, as well as safety. While each proprietary system has distinct properties that cannot be broadly applied to other systems, they all comprise the following components: • Ablation Catheter: It is a thin tube inserted through a blood vessel and navigated to the ablation zone (heart). The design of catheter highly impacts the ablation efficacy. Various types of catheters are clinically used for AF ablation, which include standard tip catheters, large tip catheters, open-loop irrigated tip catheters and closed-loop irrigated tip catheters. • Ablation Generator: It is a device designed for generating and emitting electrical pulses for the ablation procedure. The pulses created by different devices may vary in their electrical polarity and waveforms. • Mapping Software: Cardiac mapping is an electrophysiology (EP) procedure, which traces electrical impulses generated by cells of the heart. Mapping the cardiac electrical activity is a crucial component for diagnosis and treatment of arrhythmias. Pulsed field ablation for the treatment of atrial fibrillation is a minimally invasive procedure that utilizes a catheter, an ablation generator and is often used in combination with a mapping system. Further, the catheter used for the procedure can either be an ablation catheter or ablation and mapping integrated catheter. The integrated catheters eliminate the need for catheter exchange. In addition, the catheter tip configuration can vary as per the need of the procedure. The majority of the recently developed catheters have flower and basket, spherical or linear configuration, which aids the catheter to ablate specific regions of the heart with ease. Another important parameter is the diameter of the catheter, which should preferably be less. A smaller catheter diameter would lead to the formation of a minute transseptal puncture, which can be healed quickly. It is worth highlighting that the lesions formed by short bursts of electric current dissipated by the PFA catheter tip create transmural lesions (completely penetrates the heart tissue), thereby increasing the efficacy of the procedure. Pulsed-field ablation is a promising technique for the treatment of atrial fibrillation. This innovative technology has been proven to be effective and safe in treating patients affected by AF. Studies suggest that PFA is a promising technology for electricity induced pulmonary vein isolation and myocardial ablation, which results in remarkable lesion durability and safety. Various experimental cardiac and non-cardiac studies have demonstrated that the majority of the side effects associated with thermal catheter ablation are not evident with pulsed field ablation. Further, a number of PFA systems have demonstrated the ability to achieve acute electrical isolation, sub-threshold dosing or gaps in the lesion set, which can result in eroding durability over time. Research Methodology Our analysts have performed an accurate examination of the various aspects of the global market leveraging avant-garde primary and secondary sources of data collection. The report has gathered the necessary data and information from several reliable sources. Additionally, the report offers many strategic recommendations for companies involved in this ever-growing business sector to help them attain a competitive edge in the Pulsed Field Ablation Market. Thank you for reading our report. Kindly get in touch with us to know more about the report or to receive a customized copy of it. Our team will ensure the report is tailored according to your needs. To view more details on this report, click on the link https://www.rootsanalysis.com/reports/pulsed-field-ablation-market.html About Roots Analysis Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights. 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